Description:

The 1-(2,5-dioxocyclopent-3-en-1-yl)-3-oxo-7,10,13,16-tetraoxa-4 is a bifunctional PEG derivative that can be used to modify proteins, peptides and other materials.

It can react with alkyne in aqueous solution catalyzed by copper.

It can also be reduced into amine group easily while another functional group can be react with other molecules or functional groups.

PEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins.

It can also suppress the non-specific binding of charged molecules to the modified surfaces.

Application:

Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.