MS-PEG2-MS (CAS No.: 34604-52-9) is a PEG-based PROTAC linker. Its structure consists of two methanesulfonate groups connected by a dimeric ethylene glycol chain, with a molecular formula of C₈H₁₈O₈S₂ and a molecular weight of 306.35. The production process employs chemical synthesis, where methanesulfonate groups are precisely introduced at both ends of the ethylene glycol chain via methanesulfonation reactions. This mature technology allows for scalable preparation. The product is primarily used in the construction of PROTAC molecules, which connect E3 ubiquitin ligase ligands to target protein ligands, inducing ubiquitination and degradation of the target protein. It holds significant application value in cancer targeted therapy and research on neurodegenerative diseases.