t-Butyl 3-(hydroxypropoxyl)propanoate Product Description
**1. Product Structure**
The compound has a molecular formula of C₁₀H₂₀O₄ and a molecular weight of 204.26. It contains a tert-butyl-protected carboxylate group (-COOC(CH₃)₃) and a terminal hydroxyl group (-OH). Its structure consists of a 3-hydroxypropoxy chain linked to a propanoate backbone. The hydroxyl group can participate in subsequent derivatization reactions, and the tert-butyl ester can be deprotected to form a carboxylic acid under acidic conditions. It is commonly used in protection and activation strategies for synthetic intermediates.
**2. Production Process**
The compound is synthesized via esterification. Using 3-hydroxypropanol and tert-butyl propanoate as raw materials, condensation occurs under acidic catalyst (e.g., sulfuric acid) or enzymatic catalytic conditions. High-purity product is obtained after purification (e.g., distillation, chromatographic separation). Some suppliers optimize yields through custom synthesis and provide characterization data such as proton nuclear magnetic resonance (¹H NMR) and high-performance liquid chromatography (HPLC).
**3. Application Scenarios**
As a multifunctional intermediate, it is widely applied in drug synthesis (e.g., construction of linkers in PROTAC